Aneurysm Research
Aneurysm Research
An investigation into the link between local flow patterns, modified mass transport and aneurysm formation in the cranial vasculature.
Researcher: Jennifer CostelloeThe cranial vasculature is a complicated network of vessels supplying blood to the brain through the Circle of Willis (CoW). One in two people have at least one vessel with the CoW that fails to mature resulting in widely varying flows. The most common form of arterial disease in the cranial vasculature…
Analysis of stent-graft migration after endovascular repair of abdominal aortic aneurysm.
Researcher: Dr. Timothy CorbettEndovascular repair (EVAR) of abdominal aortic aneurysms (AAA) has generated widespread interest since the procedure was first introduced in the early 1990's. During minimally invasive surgery an endoprosthesis, consisting of a woven graft sutured to metallic stents is inserted through surgically exposed…
Biomechanics of Post-operative Patient-specific Abdominal Aortic Aneurysms
Researcher: Dr. David MolonyAbdominal Aortic Aneurysm is a life threatening disease, with a high mortality rate. One of the treatments of this disease is the insertion of a stent-graft into the site of the aneurysm. This shields the diseased aneurysm wall from the pressures of the blood flow and prevents rupture. There has been…
Developing a Method of Determining Abdominal Aortic Aneurysm Geometry and Rupture Threat from Standard 2D Ultrasound Images
Researcher: Sarah GaughanAn abdominal aortic aneurysm (AAA) is a localised swelling of the lower region of the aorta, usually below the renal arteries, that is a significant cause of death in the elderly. Screening currently consists of an ultrasound technician quantifying the aortic diameter from the ultrasound image obtained.…
Improved methods of rupture prediction in Abdominal Aortic Aneurysms (AAAs)
Researcher: Siobhan O’LearyAbdominal aortic aneurysms (AAAs) are a significant cause of death and are currently the 13th leading cause of death in the USA with ~20,000 deaths per year. These aneurysms are typically asymptomatic (no symptoms) and have earned the label “silent killer.” It is generally understood that…
Pre and post‐operative monitoring of abdominal aortic aneurysm behaviour
Researcher: Brónadh LynchAbdominal aortic aneurysms (AAA) are a significant clinical problem with a high incidence of mortality. Modern treatment of AAA now frequently involves the minimally invasive placement of a stent graft in the aneurysm sac to protect the patient from the risk of rupture. The devices are subject to significant…
Rupture Behaviour of Abdominal Aortic Aneurysms: A Computational and Experimental Investigation
Researcher: Dr. Barry DoylePhD PROJECT DESCRIPTIONComputational methods are utilised to examine some of the various parameters that may contribute to the overall rupture risk of abdominal aortic aneurysms (AAA). 3D reconstruction software allows computed tomography (CT) scan data of these diseased vessels to be examined using…
The Development of a Strain Rupture Index for the Prediction of Abdominal Aortic Aneurysm Failure
Researcher: Áine TierneyAbdominal Aortic Aneurysms (AAA) is one of the leading causes of death in the western world. It is characterized by structural remodeling resulting in the gradual weakening and expansion of the aortic wall. AAAs are defined to be an aorta with a diameter 1.5 times the normal infrarenal aortic diameter.…