Cardiovascular Research
Cardiovascular Research
A Numerical Model to Predict Plaque Response to Carotid Artery Stenting
Researcher: Michael LawlorCarotid arteries are located on either side of the neck and serve as the main conduit for blood flow to the brain. The current gold standard for treating diseased carotid arteries is endarterectomy, (Fig.1), in which plaque (Fig. 2) is removed through an invasive surgical procedure requiring general…
Haemodynamic Influences on Cellular Behaviour in Vascular Access Junctions - A Computational and Experimental Study
Researcher: Dr. Gráinne T. CarrollThe development of venous neointimal hyperplasia (VNH) and the subsequent formation of stenotic lesions is the primary cause of vascular access (VA) dysfunction in arteriovenous (AV) fistulae and AV grafts. This research examined the influence of the non-physiological haemodynamic environment within…
Investigation of the Turbulence Characteristics in the Flow through an Arterial-Venous Graft
Researcher: Leonard BrowneDialysis treatment is required when a patient suffers from End Stage Renal Disease (ESRD) resulting in loss of or poor kidney function. Haemodialysis is the removal of the subject’s blood to an extracorpal machine, which removes toxins from the blood and returns the blood to the body. To facilitate…
On the Mass Transport Behaviour of Drugs in the Treatment of Coronary Artery Disease Using Drug Eluting Stents
Researcher: Dr. Barry O’ConnellCoronary artery disease refers to the localisation of plaque within the coronary arteries of the heart. A number of procedures are available to vascular surgeons to achieve luminal patency in an occluded artery in order to restore blood flow. One surgical procedure uses a coronary artery bypass graft…
Stresses of arterial reconstructions of medium sized vessels with synthetic materials
Researcher: Dr. Michael O’DonnellAtherosclerosis is a disease of the arteries which commonly affects the coronary and the carotid arteries. But it can affect any artery of the body including the femoral artery, the main artery of the thigh, supplying blood to the groin and lower extremity. During the disease process fatty plaques build…
Study on the Baroreceptor Function in the Carotid Artery during Minimally Invasive Surgery
Researcher: John MulvihillThe development of atherosclerosis in the carotid bifurcation of the cardiovascular system has been the subject of much investigation. Carotid artery stenting is a minimally invasive surgical technique of reducing the atherosclerotic plaque within the carotid artery. However designing a new minimally…
The Analysis of Disturbed Flow in the Arteriovenous Graft Junction
Researcher: Stephen BroderickEnd Stage Renal Disease (ESRD) is an end result, when the kidneys fail to function. Ideally, a kidney transplant is the preferred treatment. The availability of a suitable donor is often the issue with this treatment. While the patient is waiting for a replacement kidney, an access site is created so…
The Effect of Carotid Angioplasty and Stenting on Cerebral Blood Perfusion
Researcher: Adrian LynchModern surgical treatment of arterial disease is moving toward minimally invasive surgery. The benefits of this type of treatment over conventional open surgery are numerous including shorter hospital stays and better patient recovery. The treatment of Carotid Artery Disease is one area that is resisting…
