Tissue Engineering Research
Tissue Engineering Research
An Investigation into the Thrombogenicity of Natural Occurring Materials in Tissue Engineering
Researcher: Dr. Anna PiterinaTissue Engineering is a relatively new and exciting area of research, combing tissue engineering techniques, materials engineering and mechanical engineering design. Tissue engineering in the treatment of a wide range of clinical disorders has shown considerable promise. However, tissue engineered vascular…
Design, Fabrication and Evaluation of Functional Tissue Engineered Scaffold
Researcher: Aidan CloonanInitially, as a Research Assistant under the supervision of Dr. Barry Doyle and Prof. Tim McGloughlin, I was involved in the experimental design, development and testing of hyperelastic silicone elastomers used as abdominal aortic aneurysm (AAA) analogues. Different material compositions and blends were…
Development of a Physiologically Mimetic Tissue Engineered Cardiovascular Graft for the Treatment of AAAs
Researcher: Laura DavisEffective arterial replacements for the minimally invasive treatment of abdominal aortic aneurysms (AAAs) are still an under-developed solution. AAAs are a permanent and irreversible dilation of the aorta which may rupture if untreated. Currently there are two treatment procedures; endovascular aneurysm…
On the Use of Urinary Bladder Matrix as a Tissue-Engineered material for the improvement of Stent Graft performance in Abdominal Aortic Aneurysms
Researcher: Dr. Anthony CallananAbdominal Aortic Aneurysm is a life threatening disease, with a high mortality rate. One of the treatments of this disease is the insertion of a stent-graft into the site of the aneurysm. This shields the diseased aneurysm wall from the pressures of the blood flow and prevents rupture. The Objective…
Performance and Characterisation of Naturally Derived Scaffold Materials for Tissue Engineering & Vascular Application
Researcher: Claire MeaneyCardiovascular disease is the leading cause of death worldwide. The majority of these pathological diseases tend to occur at regions of abnormal blood flow patterns. The cellular vessel wall is highly sensitive to changes in physiological blood flow, and responds by triggering an over aggressive healing…
Processing and Enhancement Biological Derived Biomaterials (ECM) for use in Regenerative Medicine and In Vitro Physiology
Researcher: Rory MooneyCurrently decellurised techniques are in use in the clinical arena for applications such as organ transplantation and replacement. This approach has enormous potential in vascular pathology reparation. Despite significant advances in this field such as chemotactic progenitor cells, resistance to bacterial…
Xenogenic extracellular matrices as potential biomaterials for interposition grafting in urological surgery
Researcher: Dr. Niall DavisThe field of tissue engineering focuses on developing strategies for reconstructing injured, diseased, and congenitally absent tissues and organs. During the last decade urologists have benefited from remodeling and regenerative properties of bioscaffolds derived from xenogenic extracellular matrices